Industry 4.0 approaches have gained increasing relevance to ensure sustainable growth and long-term competitiveness. Thereby, both logistics research and practical applications often neglect the importance of human skills development by primarily focusing on emerging technologies. Nevertheless, the structured development of employees’ competences is one of the most important requirements for a successful implementation of Industry 4.0 strategies. This paper systematically evaluates a variety of conventional as well as modern teaching and learning methods for industrial logistics engineering education in the context of Industry 4.0. As such, a comparison of methods is presented and validated by using a systematic literature review as a research methodology. The identified methods are used to guarantee and/or extend quality assurance and, individual as well as collective, professional development in industrial logistics engineering education. Moreover, the authors have conducted a laboratory experiment for industrial logistics engineering education to evaluate the learning outcomes of lectures and a form of group work as two exemplary teaching and learning methods.